Khoom Description
Dab tsi yogBrimonidine Tartrate?
Brimonidine Tartrate hmoov yogib-blocker bulk tshuaj. Nws lub npe tshuaj yog [4-({2}}(Tert-butylamino-ethoxy) phenyl] hydrogen ester, nws cov tshuaj formula yog C20H28BrNO4, nws tus txheeb ze molecular hnyav yog 437.35, CAS naj npawb yog 70359-46-5. Nws daim ntawv crystalline yog dawb los yog lub teeb daj crystalline hmoov, tsw tsw. Yuav luag insoluble hauv dej, soluble hauv ethanol thiab methanol.Brimonidine TartrateAPINws yog siv los kho qhov qhib-angle glaucoma, ocular hypertension, thiab ocular hypertension tom qab laser phais ntawm lub anterior ntu. Nov yog keeb kwm ntawm nws qhov kev tshawb pom:
Thaum xyoo 1980s, Alcon, ib lub tuam txhab American biotechnology, pib ua haujlwm ntawm alpha2-adrenergic receptor agonists. Lawv vam tias nws tuaj yeem txo qhov siab ntawm lub qhov muag los ntawm kev ua kom cov alpha2-receptor thiab muab ib hom tshuaj tshiab los kho glaucoma.
Hauv kev tshuaj xyuas cov tshuaj sib xyaw ua ke, Alcon cov kws tshawb fawb tau txheeb xyuas qhov sib xyaw hu ua UK14304 uas ua rau muaj txiaj ntsig zoo rau alpha2-receptor los kho glaucoma. Tom qab ntawd lawv tau ua tiav cov tshuaj ntsuam xyuas ntxiv thiab kev ua kom zoo ntawm cov khoom sib txuas, thiab ua tiav cov khoom sib txuas ruaj khov thiab xaiv, Brimonidine Tartrate.
Hauv xyoo 1996, nws tau pom zoo los ntawm Tebchaws Meskas FDA ua kev kho mob glaucoma. Txij thaum ntawd los, nws tau maj mam tau txais koob meej thiab tau siv dav hauv kev kho mob.
Cov ntaub ntawv tseem ceeb:
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Khoom npe |
Brimonidine Tartrate |
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tshuaj npe |
[4-(2-(Tert-butylamino-ethoxy) phenyl] hydrogen ester |
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CAS |
70359-46-5 |
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MF |
C15H16BrN5O6 |
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MW |
442.22 |
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EINECS |
629-848-5 |
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MDL Nr. |
TIAB SA 07773072 |
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Melting point |
207-208 degree (dec.) |
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Purity |
99 feem pua |
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Kev ruaj ntseg |
Hygroscopic |
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solubility |
DMSO: 1 mg/ml; PBS (pH 7.2): 3 mg/ml |
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Daim ntawv thov |
Qib tshuaj los yog lub hom phiaj tshawb fawb |
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Ntim |
Raws li koj qhov kev thov |
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Cia |
Khaws nyob rau hauv nruj, lub teeb-resistant ntim nyob rau hauv ib qhov chaw txias Khaws rau hauv lub tub yees, qis dua -20 degree |
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Cov qauv qauv |
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Cov qauv zoo:
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Cov khoom |
Specifications |
Cov txiaj ntsig |
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Qhov tshwm sim |
Dawb los yog me ntsis yellowish los yog me ntsis brownish hmoov |
Ua raws |
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Kev txheeb xyuas |
A. Kev hloov kho qhov muag tshwj xeeb |
Ua raws |
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B. Infrared absorption spectrophotometric |
Ua raws |
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Solubility |
Soluble nyob rau hauv dej, xyaum insoluble nyob rau hauv anhydrous |
Ua raws |
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ethanol thiab hauv toluene |
Ua raws |
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Specific Optical Rotation |
ntxiv rau 9.0 degree - ntxiv rau 10.5 degree |
ntxiv rau 9.9 degree |
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Poob rau ziab |
Tsawg dua lossis sib npaug rau 0.5 feem pua |
0.2 feem pua |
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Sulfated tshauv |
S0.2 feem pua |
0.1 feem pua |
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Hnyav Hlau |
Tsawg dua lossis sib npaug li 20ppm |
Ua raws |
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Yam khoom muaj feem |
Specified impurities: (imidazolidin2ylidene)quinoxalin-6-amine Tsawg dua lossis sib npaug rau 0.1 feem pua bromoquinoxalin{{0}}amine Tsawg dua lossis sib npaug li 0.1 feem pua Quinoxalin{{0}}amine Tsawg dua lossis sib npaug li 0.1 feem pua ({{0}}bromoquinoxalin-6-yl)thiourea Tsawg dua lossis sib npaug rau 0.1 feem pua ({0}}bromoquinoxalin6yl)guanidine Tsawg dua lossis sib npaug rau 0.1 feem pua {{0}}bromo-N-(1H-imidazol-2-yl)Quinoxalin-6-amine Tsawg dua los yog sib npaug rau 0.1 feem pua {{0}}(2-aminoethyl)-3-(5-bromoquinoxalin-6-yl) urea Tsawg dua lossis sib npaug li 0.1 feem pua Unspecified impurities Tsawg dua los yog sib npaug rau 0.1 feem pua Tag Nrho Tsawg dua lossis sib npaug rau 0.2 feem pua |
Ua raws Ua raws Ua raws Ua raws Ua raws Ua raws Ua raws Ua raws 0.15 feem pua |
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Assay (Rau Dried Basis) |
99. 0 feem pua - 101 |
99.9% ua |
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Xaus |
Cov khoom ua raws li Standard BP2015 |
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Muaj nuj nqi thiab kev siv:
Brimonidine Tartrate hmoovyog siv dav hauv kev kho mob. Nws cov ntawv thov tseem ceeb suav nrog cov hauv qab no:
Bronchodilator: nws tuaj yeem tsim cov bronchodilation los ntawm kev ua ntawm beta -2 receptors nyob rau hauv cov nqaij mos ntawm lub bronchi, yog li txo cov tsos mob ntawm cov kab mob ua pa xws li mob hawb pob thiab COPD.
Anti-inflammatory nyhuv: nws muaj peev xwm inhibit qhov tso tawm thiab chemotaxis ntawm inflammatory hlwb, yog li txo inflammatory tshwm sim los ntawm cov kab mob ua pa.
Antitussive effect: nws muaj cov nyhuv antitussive, uas tuaj yeem pab txo cov hnoos qeev los ntawm cov kab mob ua pa sab saud.
Thov nco ntsoov tias 'cov khoom no yog cov khoom siv raw rau kev lag luamlos yogtshawb fawb xwb, tsis yog tus kheej noj'. Peb lub tuam txhab yuav tsis muaj lub luag haujlwm rau kev pheej hmoo lossis qhov tshwm sim los ntawm kev siv tus kheej.
Packing & shipping
Ntim:
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1 ~ 2 kg |
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2-10kg |
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10-25kg |
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Peb muaj kev pabcuam customized, peb tuaj yeem ntim peb cov khoom raws li kev cai xav tau.
Yog tias koj xav paub ntau ntxiv, thov hu ncaj qha rau peb!
Shipping:
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Tsawg dua los yog sib npaug li 50 kg |
Los ntawm kev nthuav qhia qhov rooj rau qhov rooj Fedex, DHL, UPS, TNT, EMS thiab lwm yam. Ceev thiab yooj yim |
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50kg-200kg |
Los ntawm huab cua Ceev thiab pheej yig |
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Ntau tshaj lossis sib npaug li 200kg |
Los ntawm hiav txwv Txoj kev pheej yig tshaj |
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Los yog raws li koj yuav tsum tau xaiv txoj kev pheej yig tshaj los yog ceev. |
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Lub sijhawm them nyiaj
Vim li cas thiaj xaiv Xi'an Yihui
Peb lub tuam txhab yog cov kws tshaj lij kev lag luam koom nrog kev tsim khoom thiab muag cov khoom siv tshuaj thiab cov tshuaj zoo. Peb cov khoom muaj qhov zoo hauv qab no:
Cov txiaj ntsig zoo: Xi'an Yihui txais cov thev naus laus zis thiab kev tswj hwm nruj kom ntseeg tau tias qhov kev coj dawb huv thiab zoo ntawm cov khoom ua tau raws li cov qauv hauv tsev thiab thoob ntiaj teb thiab cov kev cai. Nyob rau tib lub sijhawm, lub tuam txhab muaj lub chaw soj ntsuam zoo thiab ntau daim ntawv tso cai tsim tshuaj, uas tuaj yeem muab cov khoom lag luam zoo bromine homatropine methylbromide.
Cov txheej txheem kom zoo dua: Xi'an Yihui muaj cov txheej txheem ua tiav thiab cov khoom siv niaj hnub tsim, uas tuaj yeem ua tau raws li qhov xav tau ntawm cov khoom loj thiab cov khoom tsim kho. Lub tuam txhab ib txwm muab qhov tseem ceeb rau kev tsim kho tshiab thiab kev txhim kho cov txheej txheem, thiab tau cog lus los muab cov neeg siv khoom zoo dua thiab zoo dua bromine homatropine methylbromide cov khoom.
Kev pabcuam zoo: Xi'an Yihui siv cov neeg siv khoom xav tau raws li kev qhia, them nyiaj rau kev sib txuas lus thiab kev koom tes nrog cov neeg siv khoom. Lub tuam txhab muaj cov kws tshaj lij kev muag khoom thiab pab pawg neeg siv khoom, uas tuaj yeem teb rau cov neeg siv khoom xav tau thiab cov lus nug raws sijhawm thiab raug, thiab muab kev muag khoom ua ntej, muag, thiab kev pabcuam tom qab muag los muab cov neeg siv khoom nrog kev txhawb nqa thiab lav.
Hauv cov ntsiab lus, Xi'an Yihui tuam txhab ua tus kws tshaj lij99 feem pua Brimonidine Tartratehmoovtsim cov chaw tsim khoom, muaj lub zog muaj zog thiab cov cuab yeej tsim khoom siab heev, thiab tau cog lus los muab cov neeg siv khoom zoo, muaj txiaj ntsig thiab txhim khu kev qha cov khoom siv tshuaj.
Cim npe nrov: Tuam Tshoj brimonidine tartrate hmoov manufacturers, lwm tus neeg, Hoobkas
