1.Product Description
Dexamethasone sodium phosphate yog dab tsi?
Dexamethasone sodium phosphate hmoovr(DSP) yog ib hom tshuaj corticosteroid nrog cov tshuaj npe sodium (11beta,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,{ {7}}dioxopregna-1, 4-dien-21-yl phosphate. Nws yog xim tsis muaj xim lossis yuav luag tsis muaj xim crystalline hmoov nrog cov qauv molecular ntawm C22H28FNa2O8P thiab molecular hnyav ntawm 516.4 g / mol, thiab nws CAS Tsis yog2392-39-4.
Dexamethasone sodium phosphate apituaj yeem txhim kho lysosomal daim nyias nyias thiab txo qis kev tso tawm ntawm hydrolytic enzymes los ntawm lysosomes, inhibit zus tau tej cov inflammatory tshuaj xws li bradykinin, serotonin, thiab prostaglandins, nce stability ntawm mast cell granules, thiab txo qhov tso tawm ntawm histamine. Nws kuj tuaj yeem ua rau vasoconstriction, inhibit qhov kev tsiv teb tsaws ntawm leukocytes thiab macrophages sab nraud cov hlab ntsha, thiab yog li muaj cov nyhuv anti-inflammatory. Nws tuaj yeem tiv thaiv kev tiv thaiv kab mob los ntawm inhibiting macrophage muaj nuj nqi. Nws tuaj yeem cuam tshuam qhov tsim ntawm fibroblasts, uas yog qhov zoo rau kev tiv thaiv qhov txhab pob txha. Thaum siv rau hauv kev raug mob, nws tuaj yeem txo qhov caws pliav thiab tiv thaiv qhov muag. Hauv cov kab mob corneal thiab conjunctival, nws tuaj yeem inhibit lossis txo qhov tsim ntawm neovascularization. Thaum siv hauv zos hauv kev phais pob txha pob txha thiab kev kho mob ntawm myopia phais, nws tuaj yeem txo cov kev tsis lees paub thiab kev tsim caws pliav. Nws yog siv los kho ntau yam kab mob xws li kab mob autoimmune, kev ua xua, o, rheumatism, hawb pob, ophthalmology, thiab dermatology.
Cov ntaub ntawv tseem ceeb:
Khoom npe: Dexamethasone sodium phosphate
Lub npe tshuaj: sodium (11beta,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-}dioxopregna-1 , 4-dien-21-yl phosphate
Lwm lub npe: dexamethasone 21-phosphate disodium ntsev
CAS: 2392-39-4; 55203-24-2
MF: C22H28FNa2O8P
pwm: 516.4
EINECS:200-003-9
MDL No.: MDL00079105
Melting point: 233-235 degree
cia temp. 2-8 degree
Stability: ruaj khov
Tus qauv qauv:
Cov qauv zoo
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Cov khoom |
Specifications |
Cov txiaj ntsig |
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Cim |
Dawb los yog daj me ntsis, crystalline hmoov |
dawb crystalline hmoov |
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Kev txheeb xyuas |
A,B |
Ua raws |
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Dej |
(tus lej ntawm feem pua ntawm cov ntsiab lus dej thiab cawv) Tsawg dua lossis sib npaug rau 16.0% |
4.6% |
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PH |
7.5~10.5 |
8.4 |
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Kev sib hloov kho qhov muag tshwj xeeb |
+74 degree ~ +82 degree |
+78 degree |
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Cov khoom muaj feem xyuam |
Txhua yam impurity Tsawg dua lossis sib npaug rau 1.0% |
0.22% |
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Tag nrho cov impurities Tsawg dua lossis sib npaug rau 2.0% |
0.57% |
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Kev txwv ntawm phosphate ions |
Tsawg dua lossis sib npaug rau 1.0% |
Ua raws |
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Kev txwv ntawm dexamethasone |
Tsawg dua lossis sib npaug rau 1.0% |
Ua raws |
|
Cov ntsiab lus cawv |
Tsawg dua lossis sib npaug rau 8.0% |
0.0227% |
|
Cov kuab tshuaj residual |
Acetone Tsawg dua lossis sib npaug li 5000ppm |
2ppm ua |
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Methanol Tsawg dua los yog sib npaug rau 3000ppm |
19ppm ua |
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Assay |
97.0~103.0% |
99.2% |
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Xaus: cov khoom ua raws li USP |
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Pharmacokinetics:
Dexamethasone sodium phosphate APIyog cov tshuaj corticosteroid uas muaj cov yam ntxwv zoo sib xws rau hydrocortisone, tab sis nws muaj zog dua (40-50 lub sij hawm muaj zog dua li cov tshuaj tiv thaiv kab mob piv rau hydrocortisone) thiab pib ua haujlwm sai dua. Nws muaj kev phiv tsawg heev thiab tuaj yeem txhim kho lub cev ua haujlwm sai, ua rau nws tsim nyog rau kev kho mob xwm txheej ceev ntawm cov kab mob tseem ceeb. Cov tshuaj muaj zog ntawm cov piam thaj metabolism, tiv thaiv kev mob, tiv thaiv tshuaj lom, thiab tiv thaiv kev ua xua. Nws muaj qhov cuam tshuam me me ntawm kev tuav dej, khaws sodium, thiab potassium excretion. Nws pom muaj zog pituitary-adrenal suppression, yog li ua rau muaj kev cuam tshuam tsis zoo xws li edema, kub siab, thiab cov leeg tsis muaj zog. Dexamethasone sodium phosphate ua rau cov metabolism thiab hloov pauv hauv lub siab thiab raug tso tawm los ntawm cov zis los ntawm ob lub raum, yog li ntawd, cov plasma ib nrab-lub neej ntawm cov tshuaj yuav ntev rau cov neeg uas muaj lub siab tsis zoo lossis lub raum ua haujlwm. Thaum siv los ntawm kev txhaj tshuaj intramuscular, cov tshuaj tau nce mus txog cov ntshav siab tshaj plaws hauv 1 teev, thiab nws cov plasma protein khi tus nqi qis dua li lwm cov tshuaj corticosteroid.
Muaj nuj nqi
Dexamethasone sodium phosphatehmoovmuaj ntau txoj haujlwm, feem ntau suav nrog cov hauv qab no:
- Anti-inflammatory teebmeem
Nws tuaj yeem txo qis thiab tiv thaiv cov ntaub so ntswg rau qhov mob. Nyob rau theem pib ntawm tus mob mob, nws inhibits capillary permeability, leukocyte infiltration, thiab phagocytic cov tshuaj tiv thaiv, txo qhov tso tawm ntawm ntau yam inflammatory mediators, thiab li no alleviates lub zos edema tshwm sim los ntawm exudation; nyob rau tom qab theem ntawm o, nws inhibits capillary thiab fibroblast proliferation thiab collagen synthesis, tiv thaiv adhesions thiab caws pliav tsim.
2. Immunosuppressive thiab anti-allergic teebmeem
Cov tshuaj no tuaj yeem tiv thaiv lossis cuam tshuam cov tshuaj tiv thaiv kab mob hauv lub cev, ncua kev tsis haum tshuaj tiv thaiv kab mob, txo tus naj npawb ntawm T lymphocytes, monocytes, thiab eosinophils, txo cov peev txheej ntawm immunoglobulin thiab cell nto receptors, thiab inhibit synthesis thiab tso tawm ntawm interleukins, Li no txo cov kev hloov ntawm T lymphocytes mus rau hauv lymphoblasts, inhibiting pathological hloov los ntawm kev tsis haum tshuaj, xws li allergic congestion, edema, exudation, tawm pob, du nqaij spasms, thiab cellular puas. Cov tshuaj kuj txo qhov kev nkag mus ntawm lub cev tiv thaiv kab mob los ntawm cov ntaub ntawv hauv qab daus thiab tuaj yeem txo cov concentration ntawm cov khoom ntxiv thiab cov tshuaj immunoglobulins. Tsis tas li ntawd, nws tuaj yeem cuam tshuam cov kev hloov pauv tsis lees paub thiab muaj qee yam kev ua haujlwm luv luv rau cov kab mob autoimmune.
3.Kev kho mob ntawm cov kab mob ophthalmic
Nws inhibits corneal epithelial regeneration thiab muaj peev xwm inhibit los yog txo qhov tsim ntawm neovascularization nyob rau hauv corneal thiab conjunctival kab mob.
Daim ntawv thov:
Dexamethasone sodium phosphate muaj ntau yam kev siv thiab feem ntau siv rau hauv cov xwm txheej hauv qab no:
- Inflammatory kab mob: nws muaj qhov tseem ceeb los tiv thaiv kab mob hauv ntau yam kab mob xws li mob caj dab, dermatitis, thiab kev tsis haum tshuaj. Nws tuaj yeem txo qhov mob, o, thiab liab los ntawm o.
- Cov kab mob ua pa: Cov tshuaj no tau siv dav hauv kev kho cov kab mob ua pa xws li mob hawb pob, mob ntsws, thiab kab mob ntsws ntev. Nws tuaj yeem txo cov lus teb inflammatory hauv cov kab mob ua pa thiab txo cov tsos mob xws li ua pa nyuaj thiab hnoos.
- Cov kab mob hauv lub cev: nws tuaj yeem siv los kho ntau yam kab mob autoimmune xws li mob caj dab rheumatoid thiab kab mob lupus erythematosus. Nws alleviates cov tsos mob thiab chav kawm ntawm cov kab mob los ntawm suppressing kev tiv thaiv kab mob thiab txo o.
- Kev kho mob qog noj ntshav: Cov tshuaj no qhia tau hais tias muaj txiaj ntsig zoo hauv kev tawm tsam qee yam kab mob xws li leukemia thiab malignant lymphoma. Nws tuaj yeem txo cov qog cell loj hlob thiab txo cov tsos mob los ntawm suppressing o.
- Lwm yam kev siv: Ntxiv rau qhov saum toj no daim ntawv thov thaj chaw, nws kuj tseem siv tau rau kev kho mob ntawm adrenal insufficiency, adjunctive kev kho mob ntawm congestive plawv tsis ua hauj lwm, thiab kev tswj ntawm kev nyuaj siab xeev ua ntej thiab tom qab phais.
2.Packing & shipping
Ntim:
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1 ~ 2 kg |
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2-10kg |
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10-25kg |
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Shipping:
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Tsawg dua los yog sib npaug li 50 kg |
Los ntawm kev nthuav qhia qhov rooj rau qhov rooj Fedex, DHL, UPS, TNT, EMS thiab lwm yam. Ceev thiab yooj yim |
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50kg-200kg |
Los ntawm huab cua Ceev thiab pheej yig |
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Ntau tshaj lossis sib npaug li 200kg |
Los ntawm hiav txwv Txoj kev pheej yig tshaj |
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Los yog raws li koj yuav tsum tau xaiv txoj kev pheej yig tshaj los yog ceev. |
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3. Lub sijhawm them nyiaj
4.Vim li cas xaiv Xi'an Yihui?
Cov neeg siv khoom tawm tswv yim
Xi'an Yihui daim ntawv pov thawj
Xi'an Yihui tuam txhab muaj cov hauv qab no zoo:
Kev ruaj ntseg zoo: peb siv high-purity lead-free ntau lawm tshuab. Cov khoom tau dhau los ua ntau yam kev tsim khoom nruj thiab cov txheej txheem kuaj xyuas kom paub meej cov khoom zoo.
Tus nqi tsim nyog: peb muaj tus nqi tsim nyog piv rau cov khoom zoo sib xws.
Cov kev pabcuam zoo tshaj plaws: peb muaj cov kws tshaj lij kev pabcuam thiab pab pawg pabcuam tomqab muag, yog li peb tuaj yeem muab kev pabcuam kev tshaj lij thiab kev pabcuam tomqab muag los xyuas kom cov neeg siv khoom tau txais kev paub zoo tshaj plaws.
Unified hom duab: peb txais ib lub logo sib koom ua ke thiab tsim qauv ntawm cov khoom ntim, ua kom yooj yim rau cov neeg siv khoom kom paub txog lub hom phiaj thiab pab txhawb lub hom lag luam.
Xi 'an Yihui tuam txhab muag khoom, khoom siv ntau lawm
Xi'an Yihui tuam txhab muaj qib siab ntawm kev tshawb fawb thiab kev txhim kho muaj peev xwm
Xi'an Yihui Lub Tuam Txhab Advanced ntau lawm cov cuab yeej thiab thev naus laus zis
Zoo meej kev pab cuam tom qab muag
Hauv kev xaus, raws li tus kws tshaj lijDexamethasone sodium phosphatehmoovchaw tsim tshuaj paus, peb muaj advanced technology, scale kom zoo dua, qhov zoo tshaj plaws zoo, nplua nuj ntau lawm kev, thiab cov kev pab zoo heev. Cov txiaj ntsig zoo no yuav ua rau pebDexamethasone sodium phosphateAPIsawv tawm hauv kev sib tw ua lag luam thiab yeej ntau tus neeg siv khoom ntseeg siab thiab kev txhawb nqa. yog koj needDexamethasone sodium phosphate, pls feel dawb hu rau peb txhua lub sijhawm. peb yuav teb koj asap.
peb cov ntaub ntawv tiv tauj:
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