1.Product Description
Nicotinamide Adenine Dinucleotide yog dab tsi?
-Nicotinamide Adenine Dinucleotide, abbreviated liNDA +, tseem hu ua diphosphopyridine nucleotide (DPN), los yog Co dehydrogenase I los yog coenzyme I, muaj nyob rau hauv ob hom tsiaj: oxidized daim ntawv (NAD +) thiab txo daim ntawv (NADH). Daim ntawv oxidized (NAD +) muaj qhov siab tshaj plaws ntawm ultraviolet absorption ntawm 260nm thiab lees txais hydrogen atom thiab ib qho hluav taws xob los ntawm substrates los ntawm ntau yam dehydrogenases los ua daim ntawv txo qis (NADH), uas muaj qhov nqus siab tshaj plaws ntawm 340nm. NDA yog siv los ua coenzyme hauv cov tshuaj tiv thaiv redox, ua tus pub rau ADP-ribose feem hauv ADP-ribosylation cov tshuaj tiv thaiv, thiab ua tus thawj coj ntawm cyclic ADP-ribose, tus xa xov thib ob. Nws kuj tseem ua lub substrate rau cov kab mob DNA ligase thiab ib pab pawg enzymes hu ua sirtuins, uas siv NAD + tshem tawm acetyl pawg los ntawm cov proteins.
Nicotinamide adenine dinucleotide koom nrog ntau yam kev ua haujlwm physiological xws li cellular metabolism, lub zog synthesis, thiab kho DNA, thiab ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv kab mob. Nyob rau hauv ib txwm muaj mob, qhov concentration ntawm nicotinamide adenine dinucleotide nyob rau hauv lub cev tseem nyob ruaj khov, tswj cov cellular zog. Qhov concentration ntawm nicotinamide adenine dinucleotide hauv lub cev txiav txim siab txog cov txheej txheem thiab kev laus ntawm cov cellular, thiab kev txo qis hauv cov concentration tuaj yeem ua kom cov cellular aging. Cov kev tshawb fawb tau pom tias NAD + muaj kev tiv thaiv lub raum ischemic raug mob los ntawm kev phais ischemic, txo qis cov ntshav urea nitrogen thiab creatinine hauv cov ntshav, thiab tiv thaiv lub raum tubular puas. NAD + (nicotinamide adenine dinucleotide) tuaj yeem tiv thaiv lub raum ischemic raug mob thiab muaj cov ntawv thov tseem ceeb hauv kev tsim cov tshuaj tiv thaiv thiab kho lub raum ischemic raug mob. Tsis tas li ntawd, nicotinamide adenine dinucleotide muaj qee yam kev siv hauv kev npaj cov tshuaj tiv thaiv kab mob. NAD + koom nrog hauv kev tswj hwm formalin- thiab ua tiav Freund's adjuvant-induced inflammatory mob los ntawm NAD+-deacetylases SIRT1 thiab SIRT2. SIRT1 thiab SIRT2 pab txhawb rau cov nyhuv inhibitory ntawm NAD + ntawm qhov mob inflammatory los ntawm cov txheej txheem sib txawv, yog li ua rau muaj kev phom sij rau qhov mob.
Cov ntaub ntawv tseem ceeb:
Khoom npe: -Nicotinamide Adenine Dinuclotide hmoov;
NAD + Dawb Acid;
beta-Nicotinamide adenine dinucleotide hydrate;
Nicotinamide adenine dinucleotide dawb acid
CAS:53-84-9
MF: C21H27N7O14P2
MW: 663.43
EINECS:200-184-4
Purity: 99%
Stability: ruaj khov rau 2 xyoos
Daim ntawv thov: qib zaub mov lossis siv rau kev tshawb fawb.
Packing: Raws li koj qhov kev thov
Tus qauv qauv:
Cov qauv zoo:
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Cov khoom |
Kev xav tau |
Cov txiaj ntsig |
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Qhov tshwm sim |
Dawb hmoov |
Ua raws |
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Solubility |
Soluble hauv dej |
Ua raws |
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260nm thiab pH 7.5 |
(18.0±1.0) ×l03L/mole/cm |
17.8 × l03L / mole / cm |
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ε thaum txo nrog cawv dehydrogenase ntawm 340nm thiab pH 10 |
(6.3 ± {2}}.2) × l03L/mole/cm |
6.4 × l03L / mole / cm |
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Qhov sib piv ntawm pH 7.5 |
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A250/A260 |
0.83±0.03 |
0.83 |
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A280/A260 |
0.21±0.02 |
0.20 |
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Qhov sib piv thaum txo nrog cawv dehydrogenase ntawm pH 10 |
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A340/A260 |
0.43±0.01 |
0.43 |
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Dej (los ntawm KF) |
Tsawg dua los yog sib npaug li 10% |
4.8% |
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Arsenic |
Tsawg dua lossis sib npaug li 1ppm |
Kev sib haum xeeb |
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Raws li |
Tsawg dua lossis sib npaug li 1ppm |
Kev sib haum xeeb |
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Total Bilburden |
100 CFU / g |
Kev sib haum xeeb |
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Sataph aureus |
Tsis zoo |
Tsis zoo |
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Pwm |
100 CFU / g |
Kev sib haum xeeb |
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E.COLI |
Tsis zoo |
Tsis zoo |
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Salmonella |
Tsis zoo |
Tsis zoo |
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Cov ntsiab lus |
Ntau dua lossis sib npaug li 90% |
91.2% |
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Purity (HPLC) |
Ntau dua lossis sib npaug li 95% |
99.80% |
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Xaus: |
Ua raws li qhov yuav tsum tau ua. |
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Cia: |
Khaws kom qhuav thiab deb ntawm lub teeb, cia ntawm -20 degree . |
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Function thiabdaim ntawv thov:
A.-Nicotinamide Adenine Dinucleotideua raws li cofactor rau proton (tshwj xeeb yog hydrogen ion) hloov thiab koom nrog ntau cov cellular metabolic tshua. NADH lossis ntau qhov tseeb, NADH + H +, yog nws daim ntawv txo. Nws tuaj yeem txo qis thiab nqa mus txog ob lub protons (sau li NADH + H +). NAD + yog coenzyme rau dehydrogenases xws li cawv dehydrogenase (ADH), siv nyob rau hauv oxidation ntawm ethanol. Nws ua lub luag haujlwm tseem ceeb hauv glycolysis, gluconeogenesis, lub voj voog citric acid, thiab cov kab ua pa. Cov intermediates hauv cov tshuaj tiv thaiv no hloov hydrogen rau NAD, hloov mus rau NADH + H +. NADH + H + tom qab ntawd ua raws li cov neeg nqa khoom ntawm cov protons thiab ua ke ATP los ntawm kev sib txuas ntawm chemiosmotic hauv cov kab ua pa. Hais txog kev nqus, NADH + H + muaj qhov nqus siab siab ntawm 260nm thiab 340nm, thaum NAD + tsuas yog muaj qhov nqus siab siab ntawm 260nm. Qhov no yog ib qho khoom tseem ceeb uas qhia qhov txawv ntawm ob. Nws kuj tseem ua haujlwm raws li lub hauv paus ntawm lub cev rau kev ntsuas cov nqi metabolic hauv ntau qhov kev sim metabolic. Molar absorption coefficient ntawm NAD ntawm 260nm yog 1.78104 L / (molcm), thaum NADH ntawm 340nm yog 6.210³ L / (molcm).
B. nws yog ib qho tsim nyog coenzyme nyob rau hauv cov kab mob thiab yog siv rau hauv kev tshawb fawb biochemical, kev kuaj mob, tshuaj kho mob, thiab kev tshawb fawb tshuaj.
C. nws yog ib hom tshuaj coenzyme. Nws yog tsuas yog siv nyob rau hauv kev kho mob adjuvant rau kab mob plawv thiab tuaj yeem txhim kho cov tsos mob xws li mob hauv siab thiab angina. Cov tshuaj tiv thaiv tsis zoo yuav muaj xws li qhov ncauj qhuav, kiv taub hau, thiab xeev siab.
4. Nws koom nrog lub zog metabolism thiab cov tshuaj metabolism hauv lub cev, uas muaj txiaj ntsig zoo rau kev kho ntawm tes thiab rov ua dua tshiab. Nws yog siv los kho cov kab mob plawv, myocarditis, leukopenia, thiab lwm yam mob.
Stability thiab cia:
Nicotinamide adenine dinucleotide (NAD) tuaj yeem khaws cia nrog kev ruaj ntseg zoo nyob rau hauv cov xwm txheej zoo. Nov yog cov xwm txheej khaws cia dav dav thiab ceev faj:
a. Cia kub: Khaws NAD ntawm -20 degree rau -80 degree nyob rau hauv ib puag ncig khov kom ntev nws txoj sia. Ntawm cov kub no, NAD degrades ntawm tus nqi qeeb, tswj kev ua haujlwm siab dua thiab ruaj khov.
b. Zam lub teeb: nws yog qhov yooj yim rau degradation los ntawm lub teeb, tshwj xeeb tshaj yog nyob rau hauv UV raug. Yog li ntawd, thaum lub sij hawm cia, tsis txhob raug tshav ntuj ncaj qha los yog lub teeb muaj zog thiab siv cov xim tsaus nti iav vials los yog lub teeb thaiv lub hnab rau ntim.
c. Qhuav ib puag ncig: nws yog susceptible rau noo-induced decomposition. Xyuas kom meej tias ob lub thawv thiab qhov chaw cia khoom ntawm NAD qhuav kom tsis txhob ya raws.
d. Tsis txhob rov qab khov-thaw cycles: Ntau lub voj voog khov-thaw tuaj yeem cuam tshuam tsis zoo rau kev ruaj ntseg ntawm NAD. Yog li ntawd, nws raug pom zoo kom aliquot NDA rau hauv me me raws li kev xav tau kev sim, zam ntau lub voj voog khov-thaw.
Hauv cov ntsiab lus, txhawm rau tswj kev ruaj ntseg ntawm nicotinamide adenine dinucleotide, nws raug nquahu kom khaws cia rau hauv khov, tiv thaiv lub teeb, thiab qhuav, thaum tsis txhob rov qab khov-thaw mus. Txoj kev no ua rau nws txoj haujlwm thiab kev ntseeg siab.
2.Packing & shipping
Ntim:
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1 ~ 2 kg |
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2-10kg |
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10-25kg |
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Shipping:
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Tsawg dua los yog sib npaug li 50 kg |
Los ntawm kev nthuav qhia qhov rooj rau qhov rooj Fedex, DHL, UPS, TNT, EMS thiab lwm yam. Ceev thiab yooj yim |
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50kg-200kg |
Los ntawm huab cua Ceev thiab pheej yig |
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Ntau tshaj lossis sib npaug li 200kg |
Los ntawm hiav txwv Txoj kev pheej yig tshaj |
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Los yog raws li koj yuav tsum tau xaiv txoj kev pheej yig tshaj los yog ceev. |
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3. Lub sijhawm them nyiaj
4.Vim li cas xaiv Xi'an Yihui?
Xi'an Yihui tuam txhab muaj cov hauv qab no zoo:
Kev ruaj ntseg zoo: peb siv high-purity lead-free ntau lawm tshuab. Cov khoom tau dhau los ua ntau yam kev tsim khoom nruj thiab cov txheej txheem kuaj xyuas kom paub meej cov khoom zoo.
Tus nqi tsim nyog: peb muaj tus nqi tsim nyog piv rau cov khoom zoo sib xws.
Cov kev pabcuam zoo tshaj plaws: peb muaj cov kws tshaj lij kev pabcuam thiab pab pawg pabcuam tomqab muag, yog li peb tuaj yeem muab kev pabcuam kev tshaj lij thiab kev pabcuam tomqab muag los xyuas kom cov neeg siv khoom tau txais kev paub zoo tshaj plaws.
Unified hom duab: peb txais kev sib koom ua ke lub logo thiab tsim qauv ntawm cov khoom ntim, ua kom yooj yim rau cov neeg siv khoom kom paub txog lub hom phiaj thiab txhim kho lub hom lag luam.
Xi 'an Yihui tuam txhab muag khoom, khoom siv ntau lawm
Xi'an Yihui tuam txhab muaj qib siab ntawm kev tshawb fawb thiab kev txhim kho muaj peev xwm
Xi'an Yihui Lub Tuam Txhab Advanced ntau lawm cov cuab yeej thiab thev naus laus zis
Zoo meej kev pab cuam tom qab muag
Hauv kev xaus, raws li tus kws tshaj lij-Nicotinamide Adenine Dinucleotidechaw tsim tshuaj paus, peb muaj advanced technology, scale kom zoo dua, qhov zoo tshaj plaws zoo, nplua nuj ntau lawm kev, thiab cov kev pab zoo heev. Cov txiaj ntsig zoo no yuav ua rau pebNAD+sawv tawm hauv kev sib tw ua lag luam thiab yeej ntau tus neeg siv khoom ntseeg siab thiab kev txhawb nqa. Yog tias koj xav tau -Nicotinamide Adenine Dinucleotide, pls xav tiv tauj peb txhua lub sijhawm. peb yuav teb koj asap.
peb cov ntaub ntawv tiv tauj:
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Cim npe nrov: Tuam Tshoj nicotinamide adenine dinucleotide manufacturers, lwm tus neeg, Hoobkas
