1.Product Description
Idebenone yog dab tsi?
Idebenone 58186-27-9, tseem paub los ntawm nws lub npe tshuaj, 6-(10-hydroxydecyl)-2, 3-dimethoxy-5-methyl-1, 4- benzoquinone, tau tsim thiab muab tso rau hauv kev ua lag luam xyoo 1986 hauv Nyiv los ntawm Takeda Pharmaceutical Company Limited. nws yog daj crystalline lossis crystalline hmoov uas tsis muaj ntxhiab tsw. Nws yog qhov nyuaj heev rau yaj hauv dej, soluble hauv chloroform, methanol, lossis anhydrous ethanol, thiab soluble hauv ethyl acetate. Nws yog sparingly soluble hauv n-hexane.Nws txhim kho lub hlwb metabolism thiab ua haujlwm, ua rau lub hlwb muaj peev xwm siv cov piam thaj, thiab txhawb kev tsim ntawm ATP. Nws kuj tseem muaj qhov ua kom muaj txiaj ntsig ntawm kev ua haujlwm mitochondrial. Cov neurotransmitter serotonin zoo dua metabolized nyob rau hauv lub hlwb, thiab nws kuj muaj zog tiv thaiv inflammatory thiab dawb radical scavenging los.Idebenone ibFeem ntau yog siv hauv kev kho mob los kho ntau yam oxidatively induced central paj hlwb degenerative disorders, xws li Parkinson's kab mob, Alzheimer's kab mob, multi-infarct dementia, cerebral ischemia, thiab cerebral insufficiency. Tsis tas li ntawd, Friedrich's ataxia yog kho siv nws. Tsis tas li ntawd, nws tuaj yeem suav nrog hauv cov tshuaj pleev ib ce kom muaj txiaj ntsig zoo xws li dawb radical scavenging, lipid peroxidation inhibition, anti-inflammatory ua, DNA puas inhibition, photoprotection, thiab pigmentation txo.
Cov ntaub ntawv tseem ceeb:
Khoom npe: Idebenone
CAS: 58186-27-9
MF: C19H30O5
MW: 338.44
EINECS:1308068-626-2
MDL No.: MFCD00274552
Pob: 1kg / hnab; 25kg / nruas
Cia kub: chav temp.
Stability: ruaj khov rau 2 xyoos
Tus qauv qauv:
Cov qauv zoo:
|
Cov khoom |
Specifications |
Cov txiaj ntsig |
|
1. Kev tshwm sim: |
Ib tug txiv kab ntxwv daj los yog daj, crystalline hmoov. |
Ua raws |
|
2. Solubility: |
Insoluble nyob rau hauv dej, soluble heev nyob rau hauv methanol, chloroform, dawb soluble nyob rau hauv anhydrous cawv thiab ethyl acetate. |
Ua raws |
|
3. E100 cm1% |
(458--486) |
476 |
|
4. Melting Range: |
(52-55 degree) |
54 0-54.5 degree |
|
5. Poob ntawm ziab: |
(Tsis ntau tshaj 0.1%) |
0.03% |
|
6. Residue ntawm Ignition: |
(Tsis ntau tshaj 0.1%) |
0.02% |
|
7. Heavy hlau: |
(Tsis pub tshaj 10ppm) |
Ua raws |
|
8. impurities (HPLC): |
(Tsis ntau tshaj 0.8%) |
0.7% |
|
9. Residue Solvents (GC) |
Hexane Tsawg dua lossis sib npaug rau 0.029% |
Ua raws |
|
Methanol Tsawg dua lossis sib npaug rau 0.3% |
Ua raws |
|
|
Toluene Tsawg dua lossis sib npaug rau 0.089% |
Ua raws |
|
|
10. Assay (HPLC): |
(Tsis pub tsawg dua 98.5% ntawm lub hauv paus qhuav) |
99.0% |
|
Xaus: tag nrho cov khoom ua raws li cov lus qhia ntawm kev lag luam tus qauv. |
||
Function & Application
Idebenone 58186-27-9muaj ntau yam haujlwm thiab kev siv:
- Kev paub txog kev txawj ntse: nws ntseeg tias yuav pab txhim kho kev txawj ntse thiab kev muaj peev xwm kawm thaum txhim kho kev nco thiab kev mloog hauv lub hlwb.
- Kev txhim kho ntawm lub paj hlwb thiab cov teeb meem tsis zoo: Nws tuaj yeem txhim kho cov txheej txheem metabolic hauv lub hlwb thiab pab txo qis kev puas hlwb xws li Parkinson's disease, Alzheimer's disease, thiab vascular dementia.
- Antioxidant thiab dawb radical scavenging: nws muaj zog antioxidant zog, uas muaj peev xwm neutralize dawb radicals thiab txo cellular oxidative kev nyuaj siab, yog li tiv thaiv hlwb los ntawm kev puas tsuaj.
- Kev ua kom muaj zog: nws pab txhawb kev tsim cov ATP hauv lub hlwb, yog li ua kom muaj zog thiab txhim kho lub hlwb thiab cov metabolism.
- Txhim kho cov metabolism hauv neurotransmitter: Nws tuaj yeem txhim kho cov metabolism ntawm neurotransmitter serotonin thiab pab tswj kev noj qab haus huv ntawm lub paj hlwb.
- Kev kho mob hauv nruab nrab paj hlwb degenerative kab mob: nws yog dav siv nyob rau hauv kev kho mob los kho central paj hlwb degenerative kab mob txuam nrog oxidative kev nyuaj siab, xws li Parkinson's kab mob, Alzheimer's kab mob, thiab vascular dementia.
- Kev siv tshuaj pleev ib ce: nws kuj tuaj yeem siv rau hauv cov tshuaj pleev ib ce, muab cov txiaj ntsig xws li tshem tawm cov dawb radicals, inhibiting lipid peroxidation, txo qhov mob, tiv thaiv DNA puas, muab kev tiv thaiv kev tiv thaiv, thiab txo cov pigmentation.
- Thov nco ntsoov tias cov lus piav qhia saum toj no muab cov ntsiab lus ntawm kev ua haujlwm thiab kev siv ntawm Idebenone thiab tsis yog cov lus pom zoo rau kev kho mob tshwj xeeb. Yog xav paub ntxiv lossis kev siv tshwj xeeb, nws raug nquahu kom sab laj nrog kws kho mob lossis xa mus rau cov peev txheej cuam tshuam.
Txoj kev npaj
- 3,4,5-Trimethoxytoluene raug Friedel-Crafts cov tshuaj tiv thaiv los qhia txog decanoyloxyacetyl lossis nonanoyloxycarbonyl moiety. Lub resulting compound yog ces raug rau hydrolysis, txo, thiab oxidation kom tau cov khoom xav tau.
- 2,2,3,5-Tetramethoxy-1-methyl-1,4-benzoquinone reacts nrog acyl peroxide nyob rau hauv lub xub ntiag ntawm txhuas chloride los qhia ib pawg acetyloxydecyl. Kev kho qhov nruab nrab nrog HCl thiab methanol yields cov khoom xav tau. Xwb, nws tuaj yeem cuam tshuam nrog nonanoyloxycarbonyl methyl thiab tom qab txo qis nrog aluminium hydride thiab oxidized nrog ferric chloride.
- Hauv Txoj Kev 1, phosphoryl chloride yog siv los hloov cov sulfuryl chloride los yog phosphorus pentachloride los npaj acyl chloride. Cov tshuaj chlorination reagent tuaj yeem siv ncaj qha rau hauv cov tshuaj tiv thaiv tom ntej yam tsis muaj kev kho lossis distillation, ua kom yooj yim rau kev ua haujlwm thiab txhim kho cov khoom zoo. Txoj kev hluavtaws yog qhia hauv daim duab 1.
Kev ruaj khov thiab ruaj khov
Kev ruaj ntseg thiab kev cia khoom ntawm Idebenone yog raws li hauv qab no:
Stability: Idebenone kuj ruaj khov nyob rau hauv qhuav, kaw, thiab tiv thaiv los ntawm lub teeb. Txawm li cas los xij, nws yog rhiab heev rau huab cua, lub teeb, thiab kub kub. Cov huab cua ntev ntev tuaj yeem ua rau oxidation, raug rau lub teeb muaj zog tuaj yeem ua rau degradation, thiab qhov kub thiab txias tuaj yeem txo qhov ruaj khov.
Cia tej yam kev mob: Idebenone yuav tsum tau muab cia rau hauv ib tug txias, qhuav, thiab kaw lub thawv, kom deb ntawm tshav ntuj ncaj qha. Qhov ntsuas kub tau pom zoo yog feem ntau ntawm 2 degree thiab 8 degree. Tsis txhob raug kub, av noo, ib puag ncig kaj, los yog cov pa phem.
Ntim: Idebenone feem ntau ntim rau hauv lub khob ntim ntim lossis cov hnab ntawv txhuas los muab kev tiv thaiv ntxiv.
2.Packing & shipping
Ntim:
|
1 ~ 2 kg |
|
|
2-10kg |
|
|
10-25kg |
|
Shipping:
|
Tsawg dua los yog sib npaug li 50 kg |
Los ntawm kev nthuav qhia qhov rooj rau qhov rooj Fedex, DHL, UPS, TNT, EMS thiab lwm yam. Ceev thiab yooj yim |
|
|
50kg-200kg |
Los ntawm huab cua Ceev thiab pheej yig |
|
|
Ntau tshaj lossis sib npaug li 200kg |
Los ntawm hiav txwv Txoj kev pheej yig tshaj |
|
|
Los yog raws li koj yuav tsum tau xaiv txoj kev pheej yig tshaj los yog ceev. |
||
3. Lub sijhawm them nyiaj
4.Vim li cas xaiv Xi'an Yihui?
Cov neeg siv khoom tawm tswv yim
Xi'an Yihui tuam txhab muaj cov hauv qab no zoo:
Kev ruaj ntseg zoo: peb siv high-purity lead-free ntau lawm tshuab. Cov khoom tau dhau los ua ntau yam kev tsim khoom nruj thiab cov txheej txheem kuaj xyuas kom paub meej cov khoom zoo.
Tus nqi tsim nyog: peb muaj tus nqi tsim nyog piv rau cov khoom zoo sib xws.
Cov kev pabcuam zoo tshaj plaws: peb muaj cov kws tshaj lij kev pabcuam thiab pab pawg pabcuam tomqab muag, yog li peb tuaj yeem muab kev pabcuam kev tshaj lij thiab kev pabcuam tomqab muag los xyuas kom cov neeg siv khoom tau txais kev paub zoo tshaj plaws.
Unified hom duab: peb txais kev sib koom ua ke lub logo thiab tsim qauv ntawm cov khoom ntim, ua kom yooj yim rau cov neeg siv khoom kom paub txog lub hom phiaj thiab txhim kho lub hom lag luam.
Xi 'an Yihui tuam txhab muag khoom, khoom siv ntau lawm
Xi'an Yihui tuam txhab muaj qib siab ntawm kev tshawb fawb thiab kev txhim kho muaj peev xwm
Xi'an Yihui Lub Tuam Txhab Advanced ntau lawm cov cuab yeej thiab thev naus laus zis
Zoo meej kev pab cuam tom qab muag
Hauv kev xaus, raws li tus kws tshaj lijIdebenone 58186-27-9chaw tsim tshuaj paus, peb muaj advanced technology, scale kom zoo dua, qhov zoo tshaj plaws zoo, nplua nuj ntau lawm kev, thiab cov kev pab zoo heev. Cov txiaj ntsig zoo no yuav ua rau pebIdebenone ibsawv tawm hauv kev sib tw ua lag luam thiab yeej ntau tus neeg siv khoom ntseeg siab thiab kev txhawb nqa. yog koj xav tauIdebenone, pls xav tias dawb hu rau peb txhua lub sijhawm. peb yuav teb koj asap.
peb cov ntaub ntawv tiv tauj:
E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat lossis WhatsApp: 0086-17792415937
Cim npe nrov: idebenone 58186-27-9, Tuam Tshoj idebenone 58186-27-9 manufacturers, lwm tus neeg, Hoobkas
